畜禽粪便挥发性有机物的研究进展及其在动物健康诊断应用中的潜力Advance in Volatile Organic Compounds from Animal Feces and Its Application Potential to Animal Diagnosis
石海春;刘建新;王迪铭;
SHI Haichun;LIU Jianxin;WANG Diming;Collage of Animal Sciences, Zhejiang University;
摘要(Abstract):
挥发性有机物(VOCs)是养殖业粪污造成空气污染的重要源头。随着高通量测序等化学检测技术和生物信息学等生物研究技术的不断发展,深度认知粪便VOCs组成并对其进行利用成为可能。本文对VOCs的定义和来源、危害和检测方法,以及畜禽粪便VOCs在动物健康诊断中的潜在利用价值进行综述,旨在为进一步将粪便VOCs用于动物健康诊断提供理论基础。
Volatile organic compounds(VOCs) is an important fecal pollutant source leading to serious air pollution. Nowadays, with the continuous development of chemical detection techniques such as high-throughput sequencing and biological research techniques such as bioinformatics, learning fecal VOCs profiles in depth has become possible. In this paper, the definition and source, harm and detection methods of VOCs, as well as the potential utilization in animal diagnosis of manure VOCs were summarized to provide theoretical basis for application of manure VOCs as health status biomarkers for animal.
关键词(KeyWords):
畜禽粪便;挥发性有机物;危害;检测;应用
Animal manure;Volatile organic compounds;Hazards;Testing;Application
基金项目(Foundation): 国家自然科学基金(31802083);; 国家奶牛产业技术体系(CARS-36)
作者(Authors):
石海春;刘建新;王迪铭;
SHI Haichun;LIU Jianxin;WANG Diming;Collage of Animal Sciences, Zhejiang University;
DOI: 10.19556/j.0258-7033.20190418-01
参考文献(References):
- [1]张建国,曹绥进,任光增,等.奶牛场粪便对环境的污染及处理[J].北方牧业:奶牛,2009(4):32.
- [2]Shaw S L,Mitloehner F M,Wendi J,et al.Volatile organic compound emissions from dairy cows and their waste as measured by proton-transfer-reaction mass spectrometry[J].Environ Sci Technol,2007,41(4):1310-1316.
- [3]中国统计局.中国统计年鉴[M].北京:中国统计出版社,2018.
- [4]国家环境保护部.大气挥发性有机物源排放清单编制技术指南(试行)[S].2014.
- [5]USEPA.Volatile Organic Compounds'Impact on Indoor Air Quality[EB/OL].(2017-11-06)[2018-04-18].https://www.epa.gov/indoor-air-quality-iaq/volatile-organic-compounds-impactindoor-air-quality.
- [6]NRC.The Scientific basis for estimating emissions from animal feeding operations[M].National Academies:National Academies Press,2002.
- [7]NRC.Rethinking the ozone problem in urban and regional air pollution[M].National Academies:National Academies Press,1992.
- [8]Atkinson R.Atmospheric chemistry of VOCs and NOx[J].Atmos Environ,2000,34:2063-2101.
- [9]姚立,葛茂发,乔志敏,等.挥发性有机物对流层大气化学过程研究进展[J].化学通报:网络版,2006,69(1):w049:1-7.
- [10]Rule A M,Chapin A R,McCarthy S A,et al.Assessment of an aerosol treatment to improve air quality in a swine concentrated animal feeding operation(CAFO)[J].Environ Sci Technol,2005,39(24):9649-9655.
- [11]ONeill D H,Phillips V R.A review of the control of odour nuisance from livestock buildings:Part 3,properties of the odorous substances which have been identified in livestock wastes or in the air around them[J].J Agric Eng Res,1992,53:23-50.
- [12]Kim Y,Jeon Y J,Yim J H,et al.Livestock manure valorization to biochemicals and energy using CO2:A case study of goat excreta[J/OL].J CO2 Util,2019,30:107-111.
- [13]朱志良,胡立志.甲苯的代谢、毒性与生物监测研究进展[J].职业医学,1995(4):44-45.
- [14]颜士勇.甲苯的神经毒性及其生物学机制研究[D].上海:第二军医大学,2004.
- [15]张翼翔,尹沙沙,袁明浩,等.郑州市春季大气挥发性有机物污染特征及源解析[J].环境科学,2019(10):1-16.
- [16]徐蓉.小鼠甲苯急性毒性实验研究[D].合肥:安徽医科大学,2006.
- [17]徐希娴,赵赞梅,毛丽君.甲苯的心脏毒性[J].中国工业医学杂志,2013(1):28-30.
- [18]于洪领,王增杰,单利.低浓度吸入甲苯对小鼠多组织氧化损伤的研究[J].中国卫生工程学,2015(3):257-259.
- [19]辛娜,刁其玉,张乃锋.粪臭素对动物的作用机理及其减少排放的有效方法[J].中国饲料,2011(8):7-9.
- [20]李彩燕,刘建新,汪以真,等.高效液相色谱法测定猪粪便细菌群作用下L-色氨酸体外代谢产物[J].中国畜牧杂志,2008,44(7):45-48.
- [21]李彩燕,刘建新,汪海峰.日粮纤维调控猪体粪臭素水平的研究进展[J].中国饲料,2007(9):13-16.
- [22]代兵,陈安国.粪臭素在家畜养殖中的危害[J].家畜生态,2004(4):205-206.
- [23]胥佰涛,徐平,沈生荣.茶多酚提取方法研究进展[J].茶叶,2007(3):143-146.
- [24]赵云荣,王世雷.植物花青素研究进展[J].安徽农业科学,2008(8):3095-3097.
- [25]Lo Y C,Koziel J A,Cai L,et al.Simultaneous chemical and sensory characterization of volatile organic compounds and semi-volatile organic compounds emitted from swine manure using solid phase microextraction and multidimensional gas chromatography-mass spectrometry-olfactometry[J].J Environ Qual,2008,37(2):521-534.
- [26]黄俊,何进,张吉斌,等.顶空固相微萃取-气相色谱/质谱法分析鉴定畜禽粪便中的挥发性有机化合物[J].色谱,2007(3):425-429.
- [27]沈玉君,张朋月,赵立欣,等.猪粪好氧发酵过程中挥发性有机物组分分析及致臭因子的确定[J].农业工程学报,2016(4):205-210.
- [28]周谈龙,尚斌,董红敏,等.中试规模猪粪堆肥挥发性有机物排放特征[J].农业工程学报,2017,33(6):192-198.
- [29]Shepherd S F,McGuire N D,De Lacy Costello B P,et al.The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients[J].J Breath Res,2014,8(2):026001.
- [30]Garner C E,Smith S,Costello B D L,et al.Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease[J].FASEB J,2007,21(8):1675-1688.
- [31]Raman M,Ahmed I,Gillevet P M,et al.Fecal microbiome and volatile organic compound metabolome in obese humans with nonalcoholic fatty liver disease[J].Clin Gastroenterol Hepatol,2013,11(7):868.
- [32]Sever A,Abd A E,Matana Y,et al.Biomarkers for detection and monitoring of B16 melanoma in mouse urine and feces[J].JBiomark,2015:1-9.
- [33]Rossi M,Aggio R,Staudacher H M,et al.Volatile organic compounds in feces associate with response to dietary intervention in patients with irritable bowel syndrome[J].Clin Gastroenterol Hepatol,2018,16(3):385-391.
- [34]Leopold J H,Hooijdonk R T V,Sterk P J,et al.Glucose prediction by analysis of exhaled metabolites-a systematic review[J].BMCAnesthesiol,2014,14(1):46.
- [35]Costello B D L E R,Ewer A K,et al.An analysis of volatiles in the headspace of the faeces of neonates[J].J Breath Res,2008,2(3):037023.
- [36]Garner C E,Ewer A K,Elasouad K,et al.Analysis of faecal volatile organic compounds in preterm infants who develop necrotising enterocolitis:a pilot study[J].J Pediatr Gastroenterol Nutr,2009,49(5):559.
- [37]Andreas B,Phillip T,Sina F,et al.In vivo volatile organic compound signatures of mycobacterium avium subsp.paratuberculosis[J/OL].PLoS One,2015,10(4):e0123980.
- [38]Ellis C K,Rice S,Maurer D,et al.Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG-vaccinated cattle prior to and after mycobacterium bovis challenge[J/OL].PLoS One,2017,12:e0179914.
- [39]Ellis C K,Volker S F,Griffin D L,et al.Use of faecal volatile organic compound analysis for ante-mortem discrimination between CWD-positive,-negative exposed,and-known negative white-tailed deer(Odocoileus virginianus)[J].Prion,2019,13(1):94-105.
- [40]Burciagarobles L O,Holland B P,Step D L,et al.Evaluation of breath biomarkers and serum haptoglobin concentration for diagnosis of bovine respiratory disease in heifers newly arrived at a feedlot[J].Am J Vet Res,2009,70(10):1291-1298.
- [41]Knobloch H,K?hler H,Commander N,et al.Volatile organic compound(VOC)analysis for disease detection:proof of principle for field studies detecting paratuberculosis and brucellosis[J].AIPConference Proceedings,2009,1137(1):195.
- [42]Mottram T T,Dobbelaar P,Schukken Y H,et al.An experiment to determine the feasibility of automatically detecting hyperketonaemia in dairy cows[J].Livest Prod Sci,1999,61(1):7-11.